2’-dG (iBu)-2’-phosphoramidite

Modify Date: 2025-08-25 12:07:52

2’-dG (iBu)-2’-phosphoramidite Structure
2’-dG (iBu)-2’-phosphoramidite structure
Common Name 2’-dG (iBu)-2’-phosphoramidite
CAS Number 157327-97-4 Molecular Weight 838.93
Density N/A Boiling Point N/A
Molecular Formula C45H55N6O8P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2’-dG (iBu)-2’-phosphoramidite


2’-dG (iBu)-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2’-dG (iBu)-2’-phosphoramidite

 2’-dG (iBu)-2’-phosphoramidite Biological Activity

Description 2’-dG (iBu)-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C45H55N6O8P
Molecular Weight 838.93
InChIKey HYHSVVSASKSIJT-VSLJMZOWSA-N
SMILES COc1ccc(C(OCC2CC(OP(OCCC#N)N(C(C)C)C(C)C)C(N3C=NC4C(=O)NC(NC(=O)C(C)C)NC43)O2)(c2ccccc2)c2ccc(OC)cc2)cc1
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