(R)-1-Boc-2-Methylpyrrolidine

Modify Date: 2025-08-25 08:54:12

(R)-1-Boc-2-Methylpyrrolidine Structure
(R)-1-Boc-2-Methylpyrrolidine structure
 Common Name (R)-1-Boc-2-Methylpyrrolidine
CAS Number 157007-54-0 Molecular Weight 185.263
Density 1.0±0.1 g/cm3 Boiling Point 234.0±9.0 °C at 760 mmHg
Molecular Formula C10H19NO2 Melting Point N/A
MSDS Chinese USA Flash Point 95.3±18.7 °C
Symbol GHS07
GHS07		 Signal Word Warning

 Names

Name (R)-tert-Butyl 2-methylpyrrolidine-1-carboxylate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 234.0±9.0 °C at 760 mmHg
Molecular Formula C10H19NO2
Molecular Weight 185.263
Flash Point 95.3±18.7 °C
Exact Mass 185.141586
PSA 29.54000
LogP 1.99
Vapour Pressure 0.1±0.5 mmHg at 25°C
Index of Refraction 1.463

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C,F,Xi
Risk Phrases R36/37/38
Safety Phrases 26
RIDADR UN 3334

 Synthetic Route

(S)-2-Iodomethyl-pyrrolidine-1-carboxylic acid tert-butyl ester structure

(S)-2-Iodomethy...

CAS#:338945-22-5

~86%

(R)-1-Boc-2-Methylpyrrolidine Structure

(R)-1-Boc-2-Met...

CAS#:157007-54-0

Literature: Ku, Yi-Yin; Pu, Yu-Ming; Grieme, Tim; Sharma, Padam; Bhatia, Ashok V.; Cowart, Marlon Tetrahedron, 2006 , vol. 62, # 18 p. 4584 - 4589
tert-butyl(2S)-2-{[(methylsulfonyl)oxy]methyl}-pyrrolidine-1-carboxylate structure

tert-butyl(2S)-...

CAS#:132482-09-8

~52%

(R)-1-Boc-2-Methylpyrrolidine Structure

(R)-1-Boc-2-Met...

CAS#:157007-54-0

Literature: Ku, Yi-Yin; Pu, Yu-Ming; Grieme, Tim; Sharma, Padam; Bhatia, Ashok V.; Cowart, Marlon Tetrahedron, 2006 , vol. 62, # 18 p. 4584 - 4589
N-Boc-L-Prolinol structure

N-Boc-L-Prolinol

CAS#:69610-40-8

~%

(R)-1-Boc-2-Methylpyrrolidine Structure

(R)-1-Boc-2-Met...

CAS#:157007-54-0

Literature: Tetrahedron, , vol. 62, # 18 p. 4584 - 4589
2-Methyl-2-propanyl 1-pyrrolidinecarboxylate structure

2-Methyl-2-prop...

CAS#:86953-79-9

Dimethyl sulfate structure

Dimethyl sulfate

CAS#:77-78-1

~%

tert-Butyl (2R)-2-methylpyrrolidine-1-carboxylate structure

tert-Butyl (2R)...

CAS#:137496-71-0

(R)-1-Boc-2-Methylpyrrolidine Structure

(R)-1-Boc-2-Met...

CAS#:157007-54-0

Literature: Organic Letters, , vol. 15, # 21 p. 5424 - 5427
Di-tert-butyl dicarbonate structure

Di-tert-butyl d...

CAS#:24424-99-5

2-Methylpyrrolidine structure

2-Methylpyrrolidine

CAS#:765-38-8

~%

(R)-1-Boc-2-Methylpyrrolidine Structure

(R)-1-Boc-2-Met...

CAS#:157007-54-0

Literature: Organic and Biomolecular Chemistry, , vol. 8, # 20 p. 4533 - 4535
Di-tert-butyl dicarbonate structure

Di-tert-butyl d...

CAS#:24424-99-5

~%

tert-Butyl (2R)-2-methylpyrrolidine-1-carboxylate structure

tert-Butyl (2R)...

CAS#:137496-71-0

(R)-1-Boc-2-Methylpyrrolidine Structure

(R)-1-Boc-2-Met...

CAS#:157007-54-0

Literature: Organic Letters, , vol. 15, # 21 p. 5424 - 5427
Boc-L-Proline structure

Boc-L-Proline

CAS#:15761-39-4

~%

(R)-1-Boc-2-Methylpyrrolidine Structure

(R)-1-Boc-2-Met...

CAS#:157007-54-0

Literature: Journal of Organic Chemistry, , vol. 71, # 11 p. 4336 - 4338
2-Methyl-2-propanyl 1-pyrrolidinecarboxylate structure

2-Methyl-2-prop...

CAS#:86953-79-9

methyl iodide structure

methyl iodide

CAS#:74-88-4

~%

tert-Butyl (2R)-2-methylpyrrolidine-1-carboxylate structure

tert-Butyl (2R)...

CAS#:137496-71-0

(R)-1-Boc-2-Methylpyrrolidine Structure

(R)-1-Boc-2-Met...

CAS#:157007-54-0

Literature: Journal of the American Chemical Society, , vol. 116, # 8 p. 3231 - 3239

 Synonyms

2-Methyl-2-propanyl (2R)-2-methyl-1-pyrrolidinecarboxylate
tert-Butyl (2R)-2-methylpyrrolidine-1-carboxylate
(R)-1-Boc-2-methylpyrrolidine
1-Pyrrolidinecarboxylic acid, 2-methyl-, 1,1-dimethylethyl ester, (2R)-
(R)-(-)-1-Boc-2-methylpyrrolidine
tert-Butyl (R)-2-methylpyrrolidine-1-carboxylate
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