Afamelanotide

Modify Date: 2025-09-18 17:21:22

Afamelanotide Structure
Afamelanotide structure
Common Name Afamelanotide
CAS Number 1566590-77-9 Molecular Weight 1706.897
Density N/A Boiling Point N/A
Molecular Formula C80H115N21O21 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Afamelanotide


Melanotan I acetate is a potent non-selective melanocortin receptor (MCR) agonist. Melanotan I acetate is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis. Melanotan I acetate can induce skin tanning by mimicking the actions of a-MSH on the melanocortin type 1 receptors (MC1R) of melanocytes. Melanotan I acetate can be used for sunlight-induced skin cancers research[1][2][3].

 Names

Name Afamelanotide

 Afamelanotide Biological Activity

Description Melanotan I acetate is a potent non-selective melanocortin receptor (MCR) agonist. Melanotan I acetate is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis. Melanotan I acetate can induce skin tanning by mimicking the actions of a-MSH on the melanocortin type 1 receptors (MC1R) of melanocytes. Melanotan I acetate can be used for sunlight-induced skin cancers research[1][2][3].
Related Catalog
References

[1]. Reid C, et al. Atypical melanocytic naevi following melanotan injection. Ir Med J. 2013 May;106(5):148-9.

[2]. Bhardwaj R, et al. Controlled-release delivery system for the alpha-MSH analog melanotan-I using poloxamer 407. J Pharm Sci. 1996 Sep;85(9):915-9.

 Chemical & Physical Properties

Molecular Formula C80H115N21O21
Molecular Weight 1706.897
Exact Mass 1705.857666
InChIKey VHLLBJXKNRAYGM-BHHWPIKXSA-N
SMILES CC(=O)O.CC(=O)O.CC(=O)O.CCCCC(NC(=O)C(CO)NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CO)NC(C)=O)C(=O)NC(CCC(=O)O)C(=O)NC(Cc1c[nH]cn1)C(=O)NC(Cc1ccccc1)C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCC(=O)NC(CCCCN)C(=O)N1CCCC1C(=O)NC(C(N)=O)C(C)C
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