Afamelanotide

Names

[ Name ]:
Afamelanotide

Biological Activity

[Description]:

Melanotan I acetate is a potent non-selective melanocortin receptor (MCR) agonist. Melanotan I acetate is a synthetic analogue of α-melanocyte stimulating hormone (α-MSH) that stimulates melanogenesis. Melanotan I acetate can induce skin tanning by mimicking the actions of a-MSH on the melanocortin type 1 receptors (MC1R) of melanocytes. Melanotan I acetate can be used for sunlight-induced skin cancers research[1][2][3].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> GPCR/G Protein >> Melanocortin Receptor

[References]

[1]. Reid C, et al. Atypical melanocytic naevi following melanotan injection. Ir Med J. 2013 May;106(5):148-9.

[2]. Bhardwaj R, et al. Controlled-release delivery system for the alpha-MSH analog melanotan-I using poloxamer 407. J Pharm Sci. 1996 Sep;85(9):915-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C₈₀H₁₁₅N₂₁O₂₁

[ Molecular Weight ]:
1706.897

[ Exact Mass ]:
1705.857666

Related Compounds

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