ZED-1227

Modify Date: 2024-01-10 18:40:19

ZED-1227 structure	Common Name	ZED-1227
	CAS Number	1542132-88-6	Molecular Weight	528.60
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₃₆N₆O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ZED-1227

ZED-1227 is a specific and oral transglutaminase 2 (TG2) inhibitor, which can block inflammation-induced TG2 expression and activity. ZED-1227 is a promising agent for the treatment of celiac disease (CeD)[1].

Name	ZED-1227

Description	ZED-1227 is a specific and oral transglutaminase 2 (TG2) inhibitor, which can block inflammation-induced TG2 expression and activity. ZED-1227 is a promising agent for the treatment of celiac disease (CeD)[1].
Related Catalog	Research Areas >> Inflammation/Immunology
Target	TG2[1]
References	[1]. Manu Encalada, et al. The Oral Transglutaminase 2 (TG2) Inhibitor Zed1227 Blocks TG2 Activity in a Mouse Model of Intestinal Inflammation. Gastroenterology. 154(6):S-490.

Molecular Formula	C₂₆H₃₆N₆O₆
Molecular Weight	528.60