ZED-1227

Names

[ Name ]:
ZED-1227

Biological Activity

[Description]:

ZED-1227 is a specific and oral transglutaminase 2 (TG2) inhibitor, which can block inflammation-induced TG2 expression and activity. ZED-1227 is a promising agent for the treatment of celiac disease (CeD)[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

[Target]

TG2[1]

[References]

[1]. Manu Encalada, et al. The Oral Transglutaminase 2 (TG2) Inhibitor Zed1227 Blocks TG2 Activity in a Mouse Model of Intestinal Inflammation. Gastroenterology. 154(6):S-490.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₆H₃₆N₆O₆

[ Molecular Weight ]:
528.60

Related Compounds

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