DL-5-Fluorotryptophan

Modify Date: 2024-01-02 18:34:38

DL-5-Fluorotryptophan Structure
DL-5-Fluorotryptophan structure
Common Name DL-5-Fluorotryptophan
CAS Number 154-08-5 Molecular Weight 222.216
Density 1.4±0.1 g/cm3 Boiling Point 450.7±45.0 °C at 760 mmHg
Molecular Formula C11H11FN2O2 Melting Point 265 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 226.4±28.7 °C

 Names

Name 5-fluorotryptophan
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 450.7±45.0 °C at 760 mmHg
Melting Point 265 °C (dec.)(lit.)
Molecular Formula C11H11FN2O2
Molecular Weight 222.216
Flash Point 226.4±28.7 °C
Exact Mass 222.080460
PSA 79.11000
LogP 1.17
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.673
Storage condition 2-8°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YN6825000
CHEMICAL NAME :
Tryptophan, 5-fluoro-, DL-
CAS REGISTRY NUMBER :
154-08-5
BEILSTEIN REFERENCE NO. :
0022753
LAST UPDATED :
199803
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C11-H11-F-N2-O2
MOLECULAR WEIGHT :
222.24
WISWESSER LINE NOTATION :
T56 BMJ D1YZVQ GF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
776 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 15,2134,1966

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi: Irritant;
Risk Phrases R36/38
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS YN6825000
HS Code 2933990090

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles28

More Articles
Hydrophobic effect and hydrogen bonds account for the improved activity of a complement inhibitor, compstatin.

J. Med. Chem. 49(15) , 4616-22, (2006)

Tryptophans at positions 4 and 7 of compstatin, a peptide complement inhibitor, are crucial for its interaction with C3. However, the nature of their involvement has not been studied to date. Here we ...

Ionization potentials of fluoroindoles and the origin of nonexponential tryptophan fluorescence decay in proteins.

J. Am. Chem. Soc. 127(11) , 4104-13, (2005)

This work reports an explanation for the unusual monoexponential fluorescence decay of 5-fluorotryptophan (5FTrp) in single-Trp mutant proteins [Broos, J.; Maddalena, F.; Hesp, B. H. J. Am. Chem. Soc....

In vivo synthesized proteins with monoexponential fluorescence decay kinetics.

J. Am. Chem. Soc. 126(1) , 22-3, (2004)

Tryptophan, when in a protein, typically shows multiexponential fluorescence decay kinetics. Complex kinetics prevents a straightforward interpretation of time-resolved fluorescence protein data, part...

 Synonyms

2-amino-3-(5-fluoro-1H-indol-3-yl)propanoic acid
5-Fluoro-DL-tryptophan
H-5-FLUORO-DL-TRP-OH
5-Fluoro D,L-tryptophan
5-fluoro-DL-Trp
5-Fluoro-D,L-tryptophan
DL-5-FLUOROTRYPTOPHAN
MFCD00005649
EINECS 205-822-5
5-Fluorotryptophan
5-Fluoro-DL-tryptophane
Tryptophan, 5-fluoro-