2',3'-dideoxy-5-fluorouridine

Modify Date: 2025-09-13 18:09:01

2',3'-dideoxy-5-fluorouridine Structure
2',3'-dideoxy-5-fluorouridine structure
 Common Name 2',3'-dideoxy-5-fluorouridine
CAS Number 15379-30-3 Molecular Weight 230.19
Density 1.67g/cm3 Boiling Point N/A
Molecular Formula C9H11FN2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2',3'-dideoxy-5-fluorouridine


2′,3′-Dideoxy-5-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 5-fluoro-1-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

 2',3'-dideoxy-5-fluorouridine Biological Activity

Description 2′,3′-Dideoxy-5-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.67g/cm3
Molecular Formula C9H11FN2O4
Molecular Weight 230.19
Exact Mass 230.07000
PSA 84.58000
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.645
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