LG-100064

Modify Date: 2025-08-26 11:46:19

LG-100064 Structure
LG-100064 structure
Common Name LG-100064
CAS Number 153559-46-7 Molecular Weight 350.45100
Density 1.095 Boiling Point 491.367ºC at 760 mmHg
Molecular Formula C23H26O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LG-100064


LG-100064 is a retinoid-X-receptor (RXR) agonist, with EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ; LG-100064 can be used in the research of cancer.

 Names

Name 4-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalene-2-carbonyl)benzoic acid
Synonym More Synonyms

 LG-100064 Biological Activity

Description LG-100064 is a retinoid-X-receptor (RXR) agonist, with EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ; LG-100064 can be used in the research of cancer.
Related Catalog
Target

EC50: 330 nM (RXRα), 200 nM (RXRβ), 260 nM (RXRγ)[1]

In Vitro LG-100064 (3-Methyl-TTNCB) is a retinoid-X-receptor (RXR) agonist, with EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ. LG-100064 shows no effect on RARα/β/γ (EC50, >10000 nM)[1].
References

[1]. Marcus F. Boehm, et al. Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors.

 Chemical & Physical Properties

Density 1.095
Boiling Point 491.367ºC at 760 mmHg
Molecular Formula C23H26O3
Molecular Weight 350.45100
Exact Mass 350.18800
PSA 54.37000
LogP 5.27320
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.558

 Safety Information

Hazard Codes Xi
HS Code 2918300090

 Customs

HS Code 2918300090
Summary 2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Synonyms

Benzoic acid,4-[(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]
4-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalene-2-carbonyl)benzoic acid
4-[(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)carbonyl]benzoic acid
4-[(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)carbonyl]benzoic acid
3-Methyl-TTNCB
QC-1681
p-[3,5,5,8,8-pentamethyl-1,2,3,4-tetrahydro-2-naphthyl-(2-carbonyl)]benzoic acid
LG-100064
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