Gavestinel
Modify Date: 2025-08-25 19:48:02
Gavestinel structure
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Common Name | Gavestinel | ||
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| CAS Number | 153436-38-5 | Molecular Weight | 397.19 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H11Cl2N2NaO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of GavestinelGavestinel (GV 150526) is a potent, selective, orally active and non-competitive antagonist of NMDA receptor. Gavestinel binds to the glycine site of the NMDA receptor, with a pKi of 8.5. Gavestinel can be used for the research of acute ischemic stroke[1]. |
| Name | sodium,3-[(E)-3-anilino-3-oxoprop-1-enyl]-4,6-dichloro-1H-indole-2-carboxylate |
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| Synonym | More Synonyms |
| Description | Gavestinel (GV 150526) is a potent, selective, orally active and non-competitive antagonist of NMDA receptor. Gavestinel binds to the glycine site of the NMDA receptor, with a pKi of 8.5. Gavestinel can be used for the research of acute ischemic stroke[1]. |
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| Related Catalog | |
| Target |
pKi: 8.5 (NMDA receptor)[1] |
| References |
| Molecular Formula | C18H11Cl2N2NaO3 |
|---|---|
| Molecular Weight | 397.19 |
| Exact Mass | 396.00400 |
| PSA | 88.51000 |
| LogP | 5.34680 |
| InChIKey | GRSDSTMFQHAESM-UHDJGPCESA-M |
| SMILES | O=C(C=Cc1c(C(=O)[O-])[nH]c2cc(Cl)cc(Cl)c12)Nc1ccccc1.[Na+] |
| UNII-80W7787JVB |
| 4,6-dichloro-3-((1E)-3-oxo-3-(phenylamino)-1-propenyl)-1H-indole-2-carboxylic acid sodium salt |
| Gavestinel sodium |