AZ-27
Modify Date: 2025-09-16 12:56:39
AZ-27 structure
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Common Name | AZ-27 | ||
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| CAS Number | 1516772-44-3 | Molecular Weight | 633.759 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 840.3±65.0 °C at 760 mmHg | |
| Molecular Formula | C36H35N5O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 462.0±34.3 °C | |
Use of AZ-27A potent non-nucleoside RSV L-protein polymerase inhibitor with EC50 of 0.01 uM and 1.3 uM for RSV A2 and RSV B-WST, respectively; exhibits high potency against the RSV A subtype (average EC50=24±9 nM) than against the B subtype (average EC50=1.0±0.28 uM); shows no cytotoxicity. |
| Name | N-Cyclopropyl-6-[4-({[2-(2-oxa-7-azaspiro[3.5]non-7-yl)-3-pyridinyl]carbonyl}amino)benzoyl]-5,6-dihydro-4H-thieno[3,2-d][1]benzazepine-2-carboxamide |
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| Synonym | More Synonyms |
| Description | A potent non-nucleoside RSV L-protein polymerase inhibitor with EC50 of 0.01 uM and 1.3 uM for RSV A2 and RSV B-WST, respectively; exhibits high potency against the RSV A subtype (average EC50=24±9 nM) than against the B subtype (average EC50=1.0±0.28 uM); shows no cytotoxicity. |
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| References | References 1. Tiong-Yip CL, et al. Antimicrob Agents Chemother. 2014 Jul;58(7):3867-73. 2. Noton SL, et al. J Virol. 2015 Aug;89(15):7786-98. 3. Deval J, et al. PLoS One. 2016 May 10;11(5):e0154097. View Related Products by Target RSV |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 840.3±65.0 °C at 760 mmHg |
| Molecular Formula | C36H35N5O4S |
| Molecular Weight | 633.759 |
| Flash Point | 462.0±34.3 °C |
| Exact Mass | 633.240967 |
| LogP | 3.71 |
| Vapour Pressure | 0.0±3.1 mmHg at 25°C |
| Index of Refraction | 1.724 |
| InChIKey | UHHHWFCTIQAQKF-UHFFFAOYSA-N |
| SMILES | O=C(NC1CC1)c1cc2c(s1)-c1ccccc1N(C(=O)c1ccc(NC(=O)c3cccnc3N3CCC4(CC3)COC4)cc1)CC2 |
| N-Cyclopropyl-6-[4-({[2-(2-oxa-7-azaspiro[3.5]non-7-yl)-3-pyridinyl]carbonyl}amino)benzoyl]-5,6-dihydro-4H-thieno[3,2-d][1]benzazepine-2-carboxamide |
| 4H-Thieno[3,2-d][1]benzazepine-2-carboxamide, N-cyclopropyl-5,6-dihydro-6-[4-[[[2-(2-oxa-7-azaspiro[3.5]non-7-yl)-3-pyridinyl]carbonyl]amino]benzoyl]- |