Name | AZ 4800 |
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Description | AZ 4800 is a potent γ-secretase modulator that reduces Aβ40 and Aβ42 levels in HEK/APPswe cells with IC50 of 26 nM and 60 nM, also decreases Aβ39, whereas increases both Aβ37 and Aβ38. |
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References | References 1. Borgegard T, et al. J Biol Chem. 2012 Apr 6;287(15):11810-9. 2. Strömberg K, et al. FEBS J. 2015 Jan;282(1):65-73. View Related Products by Target γ-secretase |
Molecular Formula | C24H29N5O3 |
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Molecular Weight | 435.528 |