Pemigatinib

Modify Date: 2024-01-11 00:15:16

Pemigatinib Structure
Pemigatinib structure
Common Name Pemigatinib
CAS Number 1513857-77-6 Molecular Weight 487.499
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C24H27F2N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Pemigatinib


Pemigatinib is a selective FGFR inhibitor in development for the treatment of patients with cholangiocarcinoma.

 Names

Name Pemigatinib
Synonym More Synonyms

 Pemigatinib Biological Activity

Description Pemigatinib is a selective FGFR inhibitor in development for the treatment of patients with cholangiocarcinoma.
Related Catalog
Target

Target: FGFR[1]

References

[1]. Arudra K, et al. Calcinosis cutis dermatologic toxicity associated with fibroblast growth factor receptor inhibitor for the treatment of Wilms tumor. J Cutan Pathol. 2018 Oct;45(10):786-790.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C24H27F2N5O4
Molecular Weight 487.499
Exact Mass 487.203125
LogP 0.66
Index of Refraction 1.620
Storage condition 2-8℃

 Synonyms

Pemigatinib
3-(2,6-Difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(4-morpholinylmethyl)-1,3,4,7-tetrahydro-2H-pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one
2H-Pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one, 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-1,3,4,7-tetrahydro-8-(4-morpholinylmethyl)-
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