1513857-77-6

1513857-77-6 structure

Name: Pemigatinib
Chemical Name: Pemigatinib
CAS Number: 1513857-77-6
Molecular Formula: C₂₄H₂₇F₂N₅O₄
Molecular Weight: 487.499
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK FGFR
Create Date: 2019-01-20 22:00:00
Modify Date: 2025-09-06 12:03:24
Pemigatinib is a selective FGFR inhibitor in development for the treatment of patients with cholangiocarcinoma.

Name	Pemigatinib
Synonyms	Pemigatinib 3-(2,6-Difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(4-morpholinylmethyl)-1,3,4,7-tetrahydro-2H-pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one 2H-Pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one, 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-1,3,4,7-tetrahydro-8-(4-morpholinylmethyl)-

Description	Pemigatinib is a selective FGFR inhibitor in development for the treatment of patients with cholangiocarcinoma.
Related Catalog	Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FGFR Research Areas >> Cancer
Target	Target: FGFR[1]
References	[1]. Arudra K, et al. Calcinosis cutis dermatologic toxicity associated with fibroblast growth factor receptor inhibitor for the treatment of Wilms tumor. J Cutan Pathol. 2018 Oct;45(10):786-790.