Trovirdine

Modify Date: 2025-08-22 12:56:14

Trovirdine structure	Common Name	Trovirdine
	CAS Number	149488-17-5	Molecular Weight	337.23800
	Density	1.539g/cm3	Boiling Point	450.6ºC at 760mmHg
	Molecular Formula	C₁₃H₁₃BrN₄S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Trovirdine

Trovirdine inhibits HIV-1 RT with an IC50 of 7 nM when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA)and dGTP as substrate.IC50 value: 7 nMTarget: HIV-1Trovirdine is currently in phase I clinical trials for potential use in thetreatment of AIDS.

Name	Trovirdine
Synonym	More Synonyms

Description	Trovirdine inhibits HIV-1 RT with an IC50 of 7 nM when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA)and dGTP as substrate.IC50 value: 7 nMTarget: HIV-1Trovirdine is currently in phase I clinical trials for potential use in thetreatment of AIDS.
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
References	[1]. Zhang, H. et al. Inhibition of human immunodeficiency virus type 1 wild-type and mutant reverse transcriptases by the phenyl ethylthiazolyl thiourea derivatives trovirdine and MSC-127. [2]. Cantrell, A.S. et al. Phenethylthiazolylthiourea (PETT) compounds as a newclass of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity relationship studies of PETT analogs.

Description

Related Catalog

Signaling Pathways >> Anti-infection >> HIV

Research Areas >> Infection

References

[1]. Zhang, H. et al. Inhibition of human immunodeficiency virus type 1 wild-type and mutant reverse transcriptases by the phenyl ethylthiazolyl thiourea derivatives trovirdine and MSC-127.

[2]. Cantrell, A.S. et al. Phenethylthiazolylthiourea (PETT) compounds as a newclass of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity relationship studies of PETT analogs.

Density	1.539g/cm3
Boiling Point	450.6ºC at 760mmHg
Molecular Formula	C₁₃H₁₃BrN₄S
Molecular Weight	337.23800
Exact Mass	336.00400
PSA	81.93000
LogP	3.23210
Appearance of Characters	light yellow solid
Vapour Pressure	2.61E-08mmHg at 25°C
Index of Refraction	1.696
InChIKey	HOCFDYZWQYGULA-UHFFFAOYSA-N
SMILES	S=C(NCCc1ccccn1)Nc1ccc(Br)cn1
Storage condition	-20℃

Thiourea,N-(5-bromo-2-pyridinyl)-N'-[2-(2-pyridinyl)ethyl]

Hi-142

LY-300046

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Trovirdine
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Trovirdine（LY300046）
Price: $500.0/100mg $900.0/250mg $1800.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Trovirdine（LY300046）
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

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Trovirdine suppliers

Price: $312/10mM*1mLinDMSO

Reference only. check more Trovirdine price

Trovirdine

Use of Trovirdine

Names

Trovirdine Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.