ML251
Modify Date: 2024-09-16 13:00:19
ML251 structure
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Common Name | ML251 | ||
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| CAS Number | 1486482-16-9 | Molecular Weight | 426.27 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C17H13Cl2N3O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ML251ML251, a potent nanomolar T. brucei and T. cruzi phosphofructokinase (PFK) inhibitor, inhibits T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for the research of parasite[1]. |
| Name | 2-(3,4-Dichlorophenyl)-N-[4-(1,2-oxazol-3-ylsulfamoyl)phenyl]acetamide |
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| Synonym | More Synonyms |
| Description | ML251, a potent nanomolar T. brucei and T. cruzi phosphofructokinase (PFK) inhibitor, inhibits T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for the research of parasite[1]. |
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| Related Catalog | |
| Target |
IC50: 0.37 μM (T. brucei PFK)[1]. IC50: 0.13 μM (T. cruzi PFK)[1] |
| In Vitro | ML251 (T. brucei; 0~33.3 μg/mL) produces modest dose-dependent toxicity[1]. Cell Cytotoxicity Assay[1] Cell Line: T. brucei Concentration: 0~33.3 μg/mL Incubation Time: Result: Dose-dependent reduction of cell viability. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Molecular Formula | C17H13Cl2N3O4S |
| Molecular Weight | 426.27 |
| Exact Mass | 425.000366 |
| LogP | 3.61 |
| Index of Refraction | 1.669 |
| Benzeneacetamide, 3,4-dichloro-N-[4-[(3-isoxazolylamino)sulfonyl]phenyl]- |