jmv 390-1

Modify Date: 2024-01-11 16:44:29

jmv 390-1 Structure
jmv 390-1 structure
Common Name jmv 390-1
CAS Number 148473-36-3 Molecular Weight 449.54
Density 1.177g/cm3 Boiling Point N/A
Molecular Formula C23H35N3O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of jmv 390-1


JMV 390-1 (Compound 6a) is a potent multipeptidase inhibitor. JMV 390-1 behaves as a full inhibitor of the major neurotensin (NT)/neuromedin N (NN) degrading enzymes in vitro with IC50 values from 30 to 60 nM. JMV 390-1 increases endogenous recovery of NT and NN from slices of mice hypothalamus depolarized with potassium[1].

 Names

Name jmv 390-1
Synonym More Synonyms

 jmv 390-1 Biological Activity

Description JMV 390-1 (Compound 6a) is a potent multipeptidase inhibitor. JMV 390-1 behaves as a full inhibitor of the major neurotensin (NT)/neuromedin N (NN) degrading enzymes in vitro with IC50 values from 30 to 60 nM. JMV 390-1 increases endogenous recovery of NT and NN from slices of mice hypothalamus depolarized with potassium[1].
Related Catalog
References

[1]. Doulut S, et al. Synthesis and analgesic effects of N-[3-[(hydroxyamino) carbonyl]-1-oxo-2(R)-benzylpropyl]-L-isoleucyl-L-leucine, a new potent inhibitor of multiple neurotensin/neuromedin N degrading enzymes. J Med Chem. 1993 May 14;36(10):1369-79.

 Chemical & Physical Properties

Density 1.177g/cm3
Molecular Formula C23H35N3O6
Molecular Weight 449.54
Exact Mass 449.25300
PSA 155.30000
LogP 4.40810
Index of Refraction 1.536

 Synonyms

(2S)-2-[[(2S,3S)-2-[[(2R)-2-benzyl-4-(hydroxyamino)-4-oxobutanoyl]amino]-3-methylpentanoyl]amino]-4-methylpentanoic acid
Jmv 390-1
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here


Get all suppliers and price by the below link:

jmv 390-1 suppliers

jmv 390-1 price

Related Compounds: More...
4-[3-[[4-[(4-methoxyphenyl)diazenyl]-5-oxo-1-(2,4,6-trichlorophenyl)-4H-pyrazol-3-yl]carbamoyl]anilino]-2-[2-methylpropanoyl(octadecyl)amino]-4-oxobutanoic acid
97171-73-8
4-Hydroxy-3,5-dimethoxybenzaldehyde azine
14414-32-5
Quaternary ammonium compounds, (C8-18 and C18-unsatd. alkyl)tris(hydroxyethyl), acetates (salts)
91721-89-0
POTASSIUM DISULFIDE)
1336-23-8
Bismuth(3+) citrate
813-93-4
1-(2-methyl-1-oxoallyl)-5-oxo-L-proline
80079-49-8
Propacetamol
66532-85-2
(2,5,6,10,11-pentabromocyclododecyl)-triphenylphosphanium,bromide
83949-31-9
2,4-Dichloro-5-fluorobenzoyl chloride
86393-34-2
2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N,5,5-trimethylhexanamido]acetic acid
2172156-88-4
2-ethyl-2-{[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}butanoic acid
2172272-20-5
(2R)-2-[(3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanamido]butanoic acid
2171239-82-8
3-[(3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N,4-dimethylpentanamido]oxolane-3-carboxylic acid
2171300-96-0
4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-{[1-(pyrimidin-2-yl)ethyl]carbamoyl}butanoic acid
2171517-08-9
6-{1-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]cyclopropanecarbonyl}-6-azaspiro[3.4]octane-8-carboxylic acid
2171934-94-2
(3S)-3-{[(benzyloxy)carbonyl]amino}-3-{bicyclo[3.1.0]hexan-3-yl}propanoic acid
2155372-07-7
2-(3-{[(Tert-butoxy)carbonyl]amino}-6-methylthian-3-yl)acetic acid
2152415-57-9
1-[N-methyl1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopropaneamido]cyclobutane-1-carboxylic acid
2171837-24-2
2-[N-tert-butyl-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]acetic acid
2172304-81-1