LY210073

Modify Date: 2025-08-27 12:31:00

LY210073 Structure
LY210073 structure
 Common Name LY210073
CAS Number 148291-65-0 Molecular Weight 516.53900
Density 1.314g/cm3 Boiling Point 775.7ºC at 760mmHg
Molecular Formula C30H28O8 Melting Point N/A
MSDS N/A Flash Point 257.2ºC

 Use of LY210073


LY210073 is a Leukotriene B4 (LTB4) receptor antagonist with an IC50 of 6.2 nM.

 Names

Name 5-(2-carboxyethyl)-6-[6-(4-methoxyphenyl)hex-5-enoxy]-9-oxoxanthene-2-carboxylic acid
Synonym More Synonyms

 LY210073 Biological Activity

Description LY210073 is a Leukotriene B4 (LTB4) receptor antagonist with an IC50 of 6.2 nM.
Related Catalog
Target

LTB4:6.2 nM (IC50)

In Vitro LY210073 is a Leukotriene B4 (LTB4) receptor antagonist with an IC50 of 6.2±0.1 nM. LY2100731 (Compound 32) appears to be one of the strongest inhibitors of LTB4 receptor binding reported so far[1].
References

[1]. Jackson WT, et al. Design, synthesis, and pharmacological evaluation of potent xanthone dicarboxylic acid leukotriene B4 receptor antagonists. J Med Chem. 1993 Jun 11;36(12):1726-34.

 Chemical & Physical Properties

Density 1.314g/cm3
Boiling Point 775.7ºC at 760mmHg
Molecular Formula C30H28O8
Molecular Weight 516.53900
Flash Point 257.2ºC
Exact Mass 516.17800
PSA 123.27000
LogP 5.93270
Vapour Pressure 2.52E-25mmHg at 25°C
Index of Refraction 1.636
Storage condition 2-8℃

 Synonyms

LY210073
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