UDM-001651

Modify Date: 2025-08-27 08:30:48

UDM-001651 Structure
UDM-001651 structure
 Common Name UDM-001651
CAS Number 1477497-01-0 Molecular Weight 513.56
Density N/A Boiling Point N/A
Molecular Formula C28H23N3O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of UDM-001651


UDM-001651 is a potent, selective, and orally bioavailable protease-activated receptor 4 (PAR4) antagonist (IC50=4 nM; Kd=1.4 nM). UDM-001651 shows antiplatelet potency (IC50=25 nM) in a γ-thrombin-induced platelet-rich plasma aggregation assay (γ-Thr PRP)[1].

 Names

Name UDM-001651

 UDM-001651 Biological Activity

Description UDM-001651 is a potent, selective, and orally bioavailable protease-activated receptor 4 (PAR4) antagonist (IC50=4 nM; Kd=1.4 nM). UDM-001651 shows antiplatelet potency (IC50=25 nM) in a γ-thrombin-induced platelet-rich plasma aggregation assay (γ-Thr PRP)[1].
Related Catalog
Target

IC50: 4 nM (PAR4)[1] Kd: 1.4 nM (PAR4)[1]

References

[1]. Miller MM, et al. Discovery of Potent Protease-Activated Receptor 4 Antagonists with in vivo Antithrombotic Efficacy. J Med Chem. 2019 Jun 27.

 Chemical & Physical Properties

Molecular Formula C28H23N3O5S
Molecular Weight 513.56
InChIKey LFOIDLOIBZFWDO-UHFFFAOYSA-N
SMILES COc1cc(OCc2cccc(OCc3ccccc3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1
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Chemsrc provides UDM-001651(CAS#:1477497-01-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of UDM-001651 are included as well.>> amp version: UDM-001651

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