TCMDC-125509

Modify Date: 2024-01-14 09:34:40

TCMDC-125509 Structure
TCMDC-125509 structure
Common Name TCMDC-125509
CAS Number 1476-98-8 Molecular Weight 362.894
Density 1.2g/cm3 Boiling Point 498.4ºC at 760mmHg
Molecular Formula C20H27ClN2O2 Melting Point 277-279ºC(lit.)
MSDS Chinese USA Flash Point 255.2ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name hydroquinidine hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2g/cm3
Boiling Point 498.4ºC at 760mmHg
Melting Point 277-279ºC(lit.)
Molecular Formula C20H27ClN2O2
Molecular Weight 362.894
Flash Point 255.2ºC
Exact Mass 362.176117
PSA 45.59000
LogP 4.13710
Vapour Pressure 9.92E-12mmHg at 25°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MX3018000
CHEMICAL NAME :
Hydroquinidine, monohydrochloride
CAS REGISTRY NUMBER :
1476-98-8
LAST UPDATED :
199312
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C20-H26-N2-O2.Cl-H

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
369 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,589,1977
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 52,2797,1992
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
32 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,589,1977
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 52,2797,1992

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases R22
Safety Phrases 36
RIDADR UN 1544
RTECS MX3018000
Packaging Group III
Hazard Class 6.1(b)

 Articles25

More Articles
Mutation in the Plasmodium falciparum CRT protein determines the stereospecific activity of antimalarial cinchona alkaloids.

Antimicrob. Agents Chemother. 56(10) , 5356-64, (2012)

The Cinchona alkaloids are quinoline aminoalcohols that occur as diastereomer pairs, typified by (-)-quinine and (+)-quinidine. The potency of (+)-isomers is greater than the (-)-isomers in vitro and ...

Modified asymmetric Strecker reaction of aldehyde with secondary amine: a protocol for the synthesis of S-clopidogrel (an antiplatelet agent).

J. Org. Chem. 77(16) , 7076-80, (2012)

A first approach for catalytic asymmetric Strecker reaction of aldehydes with a secondary amine in the presence of sodium fluoride using hydroquinine as chiral catalyst was developed. The catalytic sy...

Calculation of standard electrode potential of half reaction for benzoquinone and hydroquinone.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 65(2) , 333-9, (2006)

Geometric parameters, the vibrational frequencies and thermochemical values of benzoquinone and hydroquinone were computed using ab initio molecular orbital calculations (HF) and density function theo...

 Synonyms

hydroquinidine,monohydrochloride
Einecs 216-024-1
dihydrochinidinhydrochlorid
(9S)-6'-Methoxy-10,11-dihydrocinchonan-9-ol hydrochloride (1:1)
Hydroquinidine Hydrochloride
Hydroquindine Hydrochloride
Hydroquinidine HCl
TCMDC-125509
MFCD00135598
Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (9S)-, hydrochloride (1:1)
Dihydroquinidine Hydrochloride
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