6H05
Modify Date: 2024-01-02 16:55:53
6H05 structure
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Common Name | 6H05 | ||
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| CAS Number | 1469338-01-9 | Molecular Weight | 476.12 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 735.5±70.0 °C at 760 mmHg | |
| Molecular Formula | C20H30ClN3O2S3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 398.6±35.7 °C | |
Use of 6H056H05 is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C). IC50 value:Target: K-Ras G12C6H05 gives the greatest degree of modification, which allosterically modifies the oncogenic G12C mutant of highly homologous protein H-Ras without affecting wild-type K-Ras [1]. 6H05 can be used as an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors [2]. |
| Name | (5Z)-5-(4-Ethylbenzylidene)-3-[4-oxo-4-(10H-phenothiazin-10-yl)butyl]-2-thioxo-1,3-thiazolidin-4-one |
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| Synonym | More Synonyms |
| Description | 6H05 is a selective, and allosteric inhibitor of oncogenic mutant K-Ras(G12C). IC50 value:Target: K-Ras G12C6H05 gives the greatest degree of modification, which allosterically modifies the oncogenic G12C mutant of highly homologous protein H-Ras without affecting wild-type K-Ras [1]. 6H05 can be used as an intermediate for the synthesis of other oncogenic K-Ras(G12C) inhibitors [2]. |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
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| Boiling Point | 735.5±70.0 °C at 760 mmHg |
| Molecular Formula | C20H30ClN3O2S3 |
| Molecular Weight | 476.12 |
| Flash Point | 398.6±35.7 °C |
| LogP | 5.65 |
| Vapour Pressure | 0.0±2.4 mmHg at 25°C |
| Index of Refraction | 1.752 |
| Storage condition | 2~8°C |
| Hazard Codes | Xi |
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| 4-Thiazolidinone, 5-[(4-ethylphenyl)methylene]-3-[4-oxo-4-(10H-phenothiazin-10-yl)butyl]-2-thioxo-, (5Z)- |
| (5Z)-5-(4-Ethylbenzylidene)-3-[4-oxo-4-(10H-phenothiazin-10-yl)butyl]-2-thioxo-1,3-thiazolidin-4-one |
| 6H05 |