Terlipressin acetate salt

Modify Date: 2024-01-02 08:31:31

Terlipressin acetate salt structure	Common Name	Terlipressin acetate salt
	CAS Number	14636-12-5	Molecular Weight	1227.372
	Density	1.5±0.1 g/cm3	Boiling Point	1824.0±65.0 °C at 760 mmHg
	Molecular Formula	C₅₂H₇₄N₁₆O₁₅S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	1056.9±34.3 °C

Use of Terlipressin acetate salt

Terlipressin is a potent vasoconstrictor that acts via V1 receptors on arteriolar smooth muscle cells. Terlipressin can result in splanchnic vasoconstriction augmenting systemic arterial blood pressure with beneficial circulatory and renal effects that would be expected to also ameliorate the key pathophysiological changes responsible for the development of refractory ascites

Name	Terlipressin
Synonym	More Synonyms

Description	Terlipressin is a potent vasoconstrictor that acts via V1 receptors on arteriolar smooth muscle cells. Terlipressin can result in splanchnic vasoconstriction augmenting systemic arterial blood pressure with beneficial circulatory and renal effects that would be expected to also ameliorate the key pathophysiological changes responsible for the development of refractory ascites
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Vasopressin Receptor Research Areas >> Cardiovascular Disease Peptides
References	[1]. Jao YT et al. Refractory torsade de pointes induced by terlipressin (Glypressin). Int J Cardiol, 2016 Jul 30, 222:135-140.

Density	1.5±0.1 g/cm3
Boiling Point	1824.0±65.0 °C at 760 mmHg
Molecular Formula	C₅₂H₇₄N₁₆O₁₅S₂
Molecular Weight	1227.372
Flash Point	1056.9±34.3 °C
Exact Mass	1226.496094
PSA	563.45000
LogP	-6.75
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.664
Storage condition	-20°C

Precursor 0
DownStream 3
CAS#:63-91-2 L-Phenylalanine CAS#:60-18-4 L-Tyrosine CAS#:56-40-6 Glycine

(2S)-1-{[(4R,7S,10S,13S,16S,19R)-19-{[({[(Aminoacetyl)amino]acetyl}amino)acetyl]amino}-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-N-{(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl}pyrrolidine-2-carboxamide (non-preferred name)

Terlipressin

EINECS 238-680-8

MFCD00155450

N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin

Terlipressin Acetate