(RS)-3,5-DHPG

Modify Date: 2025-08-25 10:51:32

(RS)-3,5-DHPG Structure
(RS)-3,5-DHPG structure
Common Name (RS)-3,5-DHPG
CAS Number 146255-66-5 Molecular Weight 183.16100
Density 1.55g/cm3 Boiling Point 448.8ºC at 760mmHg
Molecular Formula C8H9NO4 Melting Point N/A
MSDS N/A Flash Point 225.2ºC

 Use of (RS)-3,5-DHPG


DHPG ((RS)-3,5-DHPG) is an amino acid, which acts as a selective and potent agonist of group I mGluR (mGluR 1 and mGluR 5), shows no effect on Group II or Group III mGluRs[1]. DHPG ((RS)-3,5-DHPG) is also an effective antagonist of mGluRs linked to phospholipase D[2].

 Names

Name (S)-3,5-dihydroxyphenylglycine
Synonym More Synonyms

 (RS)-3,5-DHPG Biological Activity

Description DHPG ((RS)-3,5-DHPG) is an amino acid, which acts as a selective and potent agonist of group I mGluR (mGluR 1 and mGluR 5), shows no effect on Group II or Group III mGluRs[1]. DHPG ((RS)-3,5-DHPG) is also an effective antagonist of mGluRs linked to phospholipase D[2].
Related Catalog
Target

mGluR 1

mGluR 5

References

[1]. Winder DG, et al. Metabotropic glutamate receptor (mGluR)-mediated potentiation of cyclic AMP responses does not require phosphoinositide hydrolysis: mediation by a group II-like mGluR. J Neurochem. 1995 Feb;64(2):592-9.

[2]. Pellegrini-Giampietro DE, et al. Pharmacological characterization of metabotropic glutamate receptors coupled to phospholipase D in the rat hippocampus. Br J Pharmacol. 1996 Jun;118(4):1035-43.

 Chemical & Physical Properties

Density 1.55g/cm3
Boiling Point 448.8ºC at 760mmHg
Molecular Formula C8H9NO4
Molecular Weight 183.16100
Flash Point 225.2ºC
Exact Mass 183.05300
PSA 103.78000
LogP 0.88250

 Synonyms

(RS)-3,5-DHPG
tert-Butylisopentanal
HEXANAL,3,5,5-TRIMETHYL
Isononylaldehyde
3,5,5-Trimethylcapronaldehyde
3,5,5,-trimethylhexanal
Hexanal,3,5,5-trimethl
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