Sophocarpine

Modify Date: 2024-01-02 19:11:17

Sophocarpine structure	Common Name	Sophocarpine
	CAS Number	145572-44-7	Molecular Weight	246.348
	Density	1.2±0.1 g/cm3	Boiling Point	425.4±45.0 °C at 760 mmHg
	Molecular Formula	C₁₅H₂₂N₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	194.0±21.1 °C

Use of Sophocarpine

Sophocarpine (monohydrate) is one of the significant alkaloid extracted from the traditional herb medicine Sophora flavescens which has many pharmacological properties such as anti-virus, anti-tumor, anti-inflammatory. Sophocarpine (monohydrate) significantly inhibits the growth of gastric cancer (GC) cells through multiple mechanisms such as induction of autophagy, activation of cell apoptosis and down-regulation of cell survival PI3K/AKT signaling pathway. Sophocarpine (monohydrate) has been demonstrated to have anti-tumor activity in various cancer cells, including hepatocellular carcinoma, prostate cancer and colorectal cancer[1].

Name	13,14-Didehydromatridin-15-one
Synonym	More Synonyms

Description	Sophocarpine (monohydrate) is one of the significant alkaloid extracted from the traditional herb medicine Sophora flavescens which has many pharmacological properties such as anti-virus, anti-tumor, anti-inflammatory. Sophocarpine (monohydrate) significantly inhibits the growth of gastric cancer (GC) cells through multiple mechanisms such as induction of autophagy, activation of cell apoptosis and down-regulation of cell survival PI3K/AKT signaling pathway. Sophocarpine (monohydrate) has been demonstrated to have anti-tumor activity in various cancer cells, including hepatocellular carcinoma, prostate cancer and colorectal cancer[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> PI3K/Akt/mTOR >> PI3K Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> PI3K/Akt/mTOR >> Akt Research Areas >> Inflammation/Immunology
Target	PI3K Akt
References	[1]. Huang Y, et al. Sophocarpine inhibits the growth of gastric cancer cells via autophagy and apoptosis. Front Biosci (Landmark Ed). 2019 Mar 1;24:616-627.

Density	1.2±0.1 g/cm3
Boiling Point	425.4±45.0 °C at 760 mmHg
Molecular Formula	C₁₅H₂₂N₂O
Molecular Weight	246.348
Flash Point	194.0±21.1 °C
Exact Mass	246.173218
PSA	23.55000
LogP	1.37
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.603

1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, 2,3,6,7,7a,8,13,13a,13b,13c-decahydro-, (7aS,13aR,13bR,13cS)-

Sophocarpine

Matridine-13-ene-15-one

Matridin-15-one, 13,14-didehydro-

Matridin-15-one, 13,14-didehydro- (9CI)

13,14-Didehydromatridin-15-one

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Sophocarpine
Price: ￥98.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Sophoridine hydrate
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Sophocarpine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Price: ￥351/10mg

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Sophocarpine

Use of Sophocarpine

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Sophocarpine Biological Activity

Chemical & Physical Properties

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