FD 12-9

Modify Date: 2024-01-12 16:31:36

FD 12-9 structure	Common Name	FD 12-9
	CAS Number	1451741-22-2	Molecular Weight	877.93
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₁H₄₇N₃O₁₁	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of FD 12-9

FD 12-9 is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively. Anti-glioblastoma activity[1].

Name	FD 12-9

Description	FD 12-9 is a flavonoid dimer, acts as a dual inhibitor of P-gp and BCRP, with EC50s of 285 nM and 0.9 nM, respectively. Anti-glioblastoma activity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Membrane Transporter/Ion Channel >> P-glycoprotein Signaling Pathways >> Membrane Transporter/Ion Channel >> BCRP
Target	EC50: 0.9 nM (BCRP), 285 nM (P-gp)[1]
References	[1]. Hu Xuesen, et al. Developing a novel strategy to treat glioblastoma : improving brain bioavailability of sorafenib with a synthetic flavonoid dimer to inhibit drug efflux in blood brain barrier.

Molecular Formula	C₅₁H₄₇N₃O₁₁
Molecular Weight	877.93