Hydrolyzed Fumonisin B1

Modify Date: 2024-01-11 15:48:45

Hydrolyzed Fumonisin B1 structure	Common Name	Hydrolyzed Fumonisin B1
	CAS Number	145040-09-1	Molecular Weight	405.61200
	Density	1.051±0.06 g/cm3(Predicted)	Boiling Point	593.8±50.0 °C(Predicted)
	Molecular Formula	C₂₂H₄₇NO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Hydrolyzed Fumonisin B1

Hydrolyzed Fumonisin B1 (Aminopentol) is the backbone and main hydrolysis product of the mycotoxin fumonisin B1 (FB1), can weakly inhibit ceramide synthase[1].

Name	(2S,3S,5R,10R,12S,14S,15R,16R)-2-amino-12,16-dimethylicosane-3,5,10,14,15-pentol
Synonym	More Synonyms

Description	Hydrolyzed Fumonisin B1 (Aminopentol) is the backbone and main hydrolysis product of the mycotoxin fumonisin B1 (FB1), can weakly inhibit ceramide synthase[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Neurological Disease
References	[1]. Collins TF, et al. Effects of aminopentol on in utero development in rats. Food Chem Toxicol. 2006 Feb;44(2):161-9. [2]. Humpf HU, et al. Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor. J Biol Chem. 1998 Jul 24;273(30):19060-4. [3]. Schmelz EM, et al. Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. Toxicol Appl Pharmacol. 1998 Feb;148(2):252-60.

Description

Hydrolyzed Fumonisin B1 (Aminopentol) is the backbone and main hydrolysis product of the mycotoxin fumonisin B1 (FB1), can weakly inhibit ceramide synthase[1].

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Neurological Disease

References

[1]. Collins TF, et al. Effects of aminopentol on in utero development in rats. Food Chem Toxicol. 2006 Feb;44(2):161-9.

[2]. Humpf HU, et al. Acylation of naturally occurring and synthetic 1-deoxysphinganines by ceramide synthase. Formation of N-palmitoyl-aminopentol produces a toxic metabolite of hydrolyzed fumonisin, AP1, and a new category of ceramide synthase inhibitor. J Biol Chem. 1998 Jul 24;273(30):19060-4.

[3]. Schmelz EM, et al. Induction of apoptosis by fumonisin B1 in HT29 cells is mediated by the accumulation of endogenous free sphingoid bases. Toxicol Appl Pharmacol. 1998 Feb;148(2):252-60.

Density	1.051±0.06 g/cm3(Predicted)
Boiling Point	593.8±50.0 °C(Predicted)
Molecular Formula	C₂₂H₄₇NO₅
Molecular Weight	405.61200
Exact Mass	405.34500
PSA	127.17000
LogP	3.03150
Vapour Pressure	1.42E-16mmHg at 25°C
Storage condition	-20°C

Aminopentol

HFB1

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: aminopentol
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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