SLP7111228 (hydrochloride)
Modify Date: 2025-08-21 23:24:29
SLP7111228 (hydrochloride) structure
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Common Name | SLP7111228 (hydrochloride) | ||
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| CAS Number | 1449768-48-2 | Molecular Weight | 419.991 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H33N5O.HCl | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SLP7111228 (hydrochloride)SLP7111228 is a potent and selective inhibitor of sphingosine kinase (SPHK) 1 with Ki values of 0.048 and >10 ��M for SPHK1 and 2, respectively. |
| Name | (2S)-2-{[3-(4-Octylphenyl)-1,2,4-oxadiazol-5-yl]methyl}-1-pyrrolidinecarboximidamide hydrochloride (1:1) |
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| Synonym | More Synonyms |
| Description | SLP7111228 is a potent and selective inhibitor of sphingosine kinase (SPHK) 1 with Ki values of 0.048 and >10 ��M for SPHK1 and 2, respectively. |
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| In Vitro | SLP7111228 is a potent and selective inhibitor of sphingosine kinase (SPHK) 1 with Ki values of 0.048 and >10 ��M for SPHK1 and 2, respectively.It induces a concentration-dependent decrease in sphingosine-1-phosphate in U937 cells but has no effect on sphingosine levels. In vivo, SLP7111228 decreases blood levels of S1P in a dose-dependent manner in rats. |
| Molecular Formula | C22H33N5O.HCl |
|---|---|
| Molecular Weight | 419.991 |
| Exact Mass | 419.245178 |
| 1-Pyrrolidinecarboximidamide, 2-[[3-(4-octylphenyl)-1,2,4-oxadiazol-5-yl]methyl]-, (2S)-, hydrochloride (1:1) |
| (2S)-2-{[3-(4-Octylphenyl)-1,2,4-oxadiazol-5-yl]methyl}-1-pyrrolidinecarboximidamide hydrochloride (1:1) |