Cu(II) protoporphyrin IX

Modify Date: 2024-01-28 09:57:42

Cu(II) protoporphyrin IX Structure
Cu(II) protoporphyrin IX structure
Common Name Cu(II) protoporphyrin IX
CAS Number 14494-37-2 Molecular Weight 624.18800
Density N/A Boiling Point N/A
Molecular Formula C34H32CuN4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Cu(II) protoporphyrin IX


Cu (II) Protoporphyrin IX is used as a negative control for Zn (II) Protoporphyrin (an inihibitor of heme oxygenase). Heme oxygenase has been implicated in tumor cell resistance to chemotherapy, reduction of free radical formation and inflammation, and associated with vascular repair[1][2][3].

 Names

Name 3-[(1Z,4Z,10Z,14Z)-18-(2-carboxyethyl)-7,12-bis(ethenyl)-3,8,13,17-tetramethylporphyrin-21,22,23,24-tetraid-2-yl]propanoic acid,copper
Synonym More Synonyms

 Cu(II) protoporphyrin IX Biological Activity

Description Cu (II) Protoporphyrin IX is used as a negative control for Zn (II) Protoporphyrin (an inihibitor of heme oxygenase). Heme oxygenase has been implicated in tumor cell resistance to chemotherapy, reduction of free radical formation and inflammation, and associated with vascular repair[1][2][3].
Related Catalog
References

[1]. Jozkowicz A, et al. Heme oxygenase-1 in tumors: is it a false friend?. Antioxid Redox Signal. 2007;9(12):2099-2117.

[2]. Abraham NG, et al. Heme oxygenase and the cardiovascular-renal system. Free Radic Biol Med. 2005;39(1):1-25.

[3]. Kim DH, et al. Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesenchymal stem cells. J Pharmacol Exp Ther. 2008;325(3):833-840.

 Chemical & Physical Properties

Molecular Formula C34H32CuN4O4
Molecular Weight 624.18800
Exact Mass 623.17200
PSA 94.32000
LogP 2.32230

 Synthetic Route

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Cu(II) protoporphyrin IX Structure

Cu(II) protopor...

CAS#:14494-37-2

Literature: Fischer, H.; Puetzer, B. Zeitschrift fuer Physiologische Chemie, 1926 , vol. 154, p. 39 - 63 Full Text Show Details Gmelin Handbook: Cu: MVol.B4, 133, page 1739 - 1741

~%

Cu(II) protoporphyrin IX Structure

Cu(II) protopor...

CAS#:14494-37-2

Literature: Bark, Ki-Min; Yang, Jeong-Im; Lee, Ho-Suk; Lee, Jee-Bum; Park, Chul-Ho; Park, Hyoung-Ryun Bulletin of the Korean Chemical Society, 2010 , vol. 31, # 6 p. 1633 - 1637

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

copper protoporphyrin IX