2-O-Benzoyl-3-O-t-butyldiphenylsilyl-L-threono lactone

Modify Date: 2025-11-02 16:44:35

2-O-Benzoyl-3-O-t-butyldiphenylsilyl-L-threono lactone Structure
2-O-Benzoyl-3-O-t-butyldiphenylsilyl-L-threono lactone structure
Common Name 2-O-Benzoyl-3-O-t-butyldiphenylsilyl-L-threono lactone
CAS Number 1446785-28-9 Molecular Weight 460.59
Density N/A Boiling Point N/A
Molecular Formula C27H28O5Si Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-O-Benzoyl-3-O-t-butyldiphenylsilyl-L-threono lactone


2-O-Benzoyl-3-O-t-butyldiphenylsilyl-L-threono lactone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2-O-Benzoyl-3-O-t-butyldiphenylsilyl-L-threono lactone

  Biological Activity

Description 2-O-Benzoyl-3-O-t-butyldiphenylsilyl-L-threono lactone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C27H28O5Si
Molecular Weight 460.59
InChIKey GUODUPSDXSKDBC-BJKOFHAPSA-N
SMILES CC(C)(C)[Si](OC1COC(=O)C1OC(=O)c1ccccc1)(c1ccccc1)c1ccccc1
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