3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine

Modify Date: 2025-08-21 13:33:26

3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine structure	Common Name	3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine
	CAS Number	1445379-59-8	Molecular Weight	360.45
	Density	1.2±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₅H₂₅FN₂O₅Si	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine

3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2'-Deoxy-3'-O-[dimethyl(2-methyl-2-propanyl)silyl]-2'-fluorouridine
Synonym	More Synonyms

Description	3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Density	1.2±0.1 g/cm3
Molecular Formula	C₁₅H₂₅FN₂O₅Si
Molecular Weight	360.45
Exact Mass	360.151672
LogP	1.78
Index of Refraction	1.519

Uridine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-

2'-Deoxy-3'-O-[dimethyl(2-methyl-2-propanyl)silyl]-2'-fluorouridine

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3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine

Use of 3'-O-(t-Butyldimethylsilyl)-2'-deoxy-2'-fluorouridine

Names

Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.