7-chloro-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one

Modify Date: 2024-01-10 13:02:11

7-chloro-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one Structure
7-chloro-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one structure
 Common Name 7-chloro-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one
CAS Number 144485-79-0 Molecular Weight 261.66400
Density 1.51g/cm3 Boiling Point 490ºC at 760mmHg
Molecular Formula C12H8ClN3O2 Melting Point N/A
MSDS N/A Flash Point 250.1ºC

 Names

Name 7-chloro-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one

 Chemical & Physical Properties

Density 1.51g/cm3
Boiling Point 490ºC at 760mmHg
Molecular Formula C12H8ClN3O2
Molecular Weight 261.66400
Flash Point 250.1ºC
Exact Mass 261.03100
PSA 60.92000
LogP 2.33550
Vapour Pressure 9.53E-10mmHg at 25°C
Index of Refraction 1.702

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VA2806010
CHEMICAL NAME :
4(3H)-Quinazolinone, 7-chloro-3-(3-methyl-5-isoxazolyl)-
CAS REGISTRY NUMBER :
144485-79-0
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C12-H8-Cl-N3-O2
MOLECULAR WEIGHT :
261.68

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - ptosis Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 47,465,1992

 Synthetic Route

4-chloro-2-nitrobenzoyl chloride structure

4-chloro-2-nitr...

CAS#:41995-04-4

~%

7-chloro-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one Structure

7-chloro-3-(3-m...

CAS#:144485-79-0

Literature: Plescia; Diadone; Raffa; Bajardi; Caruso; Cutuli; Amico-Roxas Farmaco, 1992 , vol. 47, # 4 p. 465 - 475
4-chloro-N-(3-methylisoxazol-5-yl)-2-nitrobenzamide structure

4-chloro-N-(3-m...

CAS#:144485-98-3

~%

7-chloro-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one Structure

7-chloro-3-(3-m...

CAS#:144485-79-0

Literature: Plescia; Diadone; Raffa; Bajardi; Caruso; Cutuli; Amico-Roxas Farmaco, 1992 , vol. 47, # 4 p. 465 - 475
2-amino-4-chloro-N-(3-methyl-1,2-oxazol-5-yl)benzamide structure

2-amino-4-chlor...

CAS#:144485-94-9

Triethyl orthoformate structure

Triethyl orthof...

CAS#:122-51-0

~%

7-chloro-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one Structure

7-chloro-3-(3-m...

CAS#:144485-79-0

Literature: Farmaco, , vol. 47, # 4 p. 465 - 475
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Chemsrc provides CAS#:144485-79-0 MSDS, density, melting point, boiling point, structure, etc. Its name is 7-chloro-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one>> amp version: 7-chloro-3-(3-methyl-1,2-oxazol-5-yl)quinazolin-4-one

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