Fimaporfin

Modify Date: 2025-08-27 09:12:28

Use of Fimaporfin

Fimaporfin (TPCS2a) is an endosomal/lysosomal-localizing photosensitizer[1].

Name	Fimaporfin B
Synonym	More Synonyms

Description	Fimaporfin (TPCS2a) is an endosomal/lysosomal-localizing photosensitizer[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	The endosomal/lysosomal localizing photosensitizer Fimaporfin (0.35 μg/ml) is used in the drug delivery technology photochemical internalization (PCI) in combination with drugs that usually are trapped in endosomes and/or lysosomes[1].
References	[1]. Kaja Lund, et al. 5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin. J Exp Clin Cancer Res. 2017 Dec 19;36(1):187.

Density	1.4±0.1 g/cm3
Molecular Formula	C₄₄H₃₂N₄O₆S₂
Molecular Weight	776.878
Exact Mass	776.176331
LogP	8.83
Index of Refraction	1.690
InChIKey	AINQERPKMNDVQT-UHFFFAOYSA-N
SMILES	O=S(=O)(O)c1ccc(-c2c3nc(c(-c4ccc(S(=O)(=O)O)cc4)c4ccc([nH]4)c(-c4ccccc4)c4nc(c(-c5ccccc5)c5[nH]c2CC5)C=C4)C=C3)cc1.O=S(=O)(O)c1ccc(-c2c3nc(c(-c4ccc(S(=O)(=O)O)cc4)c4ccc([nH]4)c(-c4ccccc4)c4nc(c(-c5ccccc5)c5ccc2[nH]5)C=C4)CC3)cc1.O=S(=O)(O)c1ccc(-c2c3nc(c(-c4ccc(S(=O)(=O)O)cc4)c4ccc([nH]4)c(-c4ccccc4)c4nc(c(-c5ccccc5)c5ccc2[nH]5)CC4)C=C3)cc1

4,4'-(15,20-Diphenyl-2,3-dihydroporphyrin-5,10-diyl)dibenzenesulfonic acid

Benzenesulfonic acid, 4,4'-(2,3-dihydro-15,20-diphenyl-21H,23H-porphine-5,10-diyl)bis-

Fimaporfin B

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Price: ￥3500/5 mg

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