Fimaporfin

Names

[ Name ]:
Fimaporfin

[Synonym ]:
4,4'-(15,20-Diphenyl-2,3-dihydroporphyrin-5,10-diyl)dibenzenesulfonic acid
Benzenesulfonic acid, 4,4'-(2,3-dihydro-15,20-diphenyl-21H,23H-porphine-5,10-diyl)bis-
Fimaporfin B

Biological Activity

[Description]:

Fimaporfin (TPCS2a) is an endosomal/lysosomal-localizing photosensitizer[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vitro]

The endosomal/lysosomal localizing photosensitizer Fimaporfin (0.35 μg/ml) is used in the drug delivery technology photochemical internalization (PCI) in combination with drugs that usually are trapped in endosomes and/or lysosomes[1].

[References]

[1]. Kaja Lund, et al. 5-FU resistant EMT-like pancreatic cancer cells are hypersensitive to photochemical internalization of the novel endoglin-targeting immunotoxin CD105-saporin. J Exp Clin Cancer Res. 2017 Dec 19;36(1):187.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₄₄H₃₂N₄O₆S₂

[ Molecular Weight ]:
776.878

[ Exact Mass ]:
776.176331

[ LogP ]:
8.83

[ Index of Refraction ]:
1.690

Related Compounds

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