Ledipasvir (acetone)

Modify Date: 2024-01-09 12:00:39

Ledipasvir (acetone) Structure
Ledipasvir (acetone) structure
Common Name Ledipasvir (acetone)
CAS Number 1441674-54-9 Molecular Weight 947.079
Density N/A Boiling Point N/A
Molecular Formula C52H60F2N8O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ledipasvir (acetone)


Ledipasvir acetone is the active pharmaceutical ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon.

 Names

Name Ledipasvir acetone
Synonym More Synonyms

 Ledipasvir (acetone) Biological Activity

Description Ledipasvir acetone is the active pharmaceutical ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon.
Related Catalog
In Vitro Ledipasvir acetone is considered the active pharmaceutical ingredient, which is converted to Ledipasvir spray-dried dispersion, an amorphous free base.

 Chemical & Physical Properties

Molecular Formula C52H60F2N8O7
Molecular Weight 947.079
Exact Mass 946.455322
PSA 191.71000
LogP 9.86020
Storage condition 2-8℃

 Synonyms

Ledipasvir (acetone)
Carbamic acid, N-[(1S)-1-[[(6S)-6-[5-[9,9-difluoro-7-[2-[(1R,3S,4S)-2-[(2S)-2-[(methoxycarbonyl)amino]-3-methyl-1-oxobutyl]-2-azabicyclo[2.2.1]hept-3-yl]-1H-benzimidazol-6-yl]-9H-fluoren-2-yl]-1H-imidazol-2-yl]-5-azaspiro[2.4]hept-5-yl]carbonyl]-2-methylpropyl]-, methyl ester, compd. with 2-propanone (1:1)
Ledipasvir compd. with acetone
Methyl [(2S)-1-{(1R,3S,4S)-3-[6-(9,9-difluoro-7-{2-[(6S)-5-{(2S)-2-[(methoxycarbonyl)amino]-3-methylbutanoyl}-5-azaspiro[2.4]hept-6-yl]-1H-imidazol-5-yl}-9H-fluoren-2-yl)-1H-benzimidazol-2-yl]-2-azabicyclo[2.2.1]hept-2-yl}-3-methyl-1-oxo-2-butanyl]carbamate - acetone (1:1)
Ledipasvir (GS5885) acetone