Ledipasvir diacetone
Modify Date: 2025-08-21 09:29:12
Ledipasvir diacetone structure
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Common Name | Ledipasvir diacetone | ||
|---|---|---|---|---|
| CAS Number | 1502655-48-2 | Molecular Weight | 1005.16000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C55H66F2N8O8 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Ledipasvir diacetoneLedipasvir diacetone is the active pharmaceutical ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon. |
| Name | Ledipasvir diacetone |
|---|---|
| Synonym | More Synonyms |
| Description | Ledipasvir diacetone is the active pharmaceutical ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon. |
|---|---|
| Related Catalog | |
| In Vitro | Ledipasvir diacetone is considered the active pharmaceutical ingredient, which is converted to Ledipasvir spray-dried dispersion, an amorphous free base. |
| Molecular Formula | C55H66F2N8O8 |
|---|---|
| Molecular Weight | 1005.16000 |
| Exact Mass | 1004.50000 |
| PSA | 208.78000 |
| LogP | 10.45550 |
| InChIKey | LXKDKHCANHWUPC-YGWQTYEPSA-N |
| SMILES | CC(C)=O.CC(C)=O.COC(=O)NC(C(=O)N1CC2(CC2)CC1c1ncc(-c2ccc3c(c2)C(F)(F)c2cc(-c4ccc5nc(C6C7CCC(C7)N6C(=O)C(NC(=O)OC)C(C)C)[nH]c5c4)ccc2-3)[nH]1)C(C)C |
| Storage condition | 2-8℃ |
| Methyl N-[(2S)-1-[(6S)-6-[5-[9,9-Difluoro-7-[2-[(1S,2S,4R)-3-[(2S)-2-(methoxycarbonylamino)-3-methylbutanoyl]-3-azabicyclo[2.2.1]heptan-2-yl]-3H-benzimidazol-5-yl]fluoren-2-yl]-1H-imidazol-2-yl]-5-azaspiro[2.4]heptan-5-yl]-3-methyl-1-oxobutan-2-yl]carbamate diacetone |
| GS-5885 diacetone |
| methyl ((S)-1-((S)-6-(5-(9,9-difluoro-7-(2-((1R,3S,4S)-2-((methoxycarbonyl)-L-valyl)-2-azabicyclo[2.2.1]heptan-3-yl)-1H-benzo[d]imidazol-6-yl)-9H-fluoren-2-yl)-1H-imidazol-2-yl)-5-azaspiro[2.4]heptan-5-yl)-3-methyl-1-oxobutan-2-yl)carbamate compound with propan-2-one (1:2) |
| Ledipasvir (diacetone) |