jaceidin triacetate

Modify Date: 2024-01-12 11:38:21

jaceidin triacetate Structure
jaceidin triacetate structure
Common Name jaceidin triacetate
CAS Number 14397-69-4 Molecular Weight 486.425
Density 1.4±0.1 g/cm3 Boiling Point 599.9±50.0 °C at 760 mmHg
Molecular Formula C24H22O11 Melting Point N/A
MSDS N/A Flash Point 257.5±30.2 °C

 Use of jaceidin triacetate


Jaceidin triacetate(compound 54) is a natural compound isolated formmarulabark.Jaceidin triacetatecan inhibitSARS-CoV-2 Mpro, with theIC50of 11.9μM.Jaceidin triacetateinhibits the replication of Sars-Cov-2 Viral in Vero-E6 cells[1][2].

 Names

Name 2-(4-Acetoxy-3-methoxyphenyl)-3,6-dimethoxy-4-oxo-4H-chromene-5,7 -diyl diacetate
Synonym More Synonyms

 jaceidin triacetate Biological Activity

Description Jaceidin triacetate(compound 54) is a natural compound isolated formmarulabark.Jaceidin triacetatecan inhibitSARS-CoV-2 Mpro, with theIC50of 11.9μM.Jaceidin triacetateinhibits the replication of Sars-Cov-2 Viral in Vero-E6 cells[1][2].
Related Catalog
Target

11.9 μM (SARS-CoV-2 Mpro)[2]

References

[1]. Cádiz-Gurrea ML, et al. Enhancing the Yield of Bioactive Compounds from Sclerocarya birrea Bark by Green Extraction Approaches. Molecules. 2019;24(5):966.  

[2]. Moua Yang, et al. Inhibition of Sars-Cov-2 Viral Replication and In Vivo Thrombus Formation By a Novel Plant Flavonoid. Blood. Volume 138, Supplement 1, 23 November 2021, Page 3144

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 599.9±50.0 °C at 760 mmHg
Molecular Formula C24H22O11
Molecular Weight 486.425
Flash Point 257.5±30.2 °C
Exact Mass 486.116211
PSA 136.80000
LogP 0.65
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.590

 Safety Information

Hazard Codes Xi

 Synonyms

2-(4-Acetoxy-3-methoxyphenyl)-3,6-dimethoxy-4-oxo-4H-chromene-5,7-diyl diacetate
Flavone, 4',5,7-trihydroxy-3,3',6-trimethoxy-, triacetate
4H-1-Benzopyran-4-one, 5,7-bis(acetyloxy)-2-[4-(acetyloxy)-3-methoxyphenyl]-3,6-dimethoxy-