BR103

Modify Date: 2024-01-05 15:32:10

BR103 Structure
BR103 structure
Common Name BR103
CAS Number 1434873-26-3 Molecular Weight 448.527
Density N/A Boiling Point N/A
Molecular Formula C24H28N6O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BR103


BR103 is a potent, metabolically stable and highly selective small molecule agonist of complement C3a receptor (C3aR) with EC50 of 22 ± 8  nM; displays high selectivity for C3aR over C5aR; induces paw oedema and mast cell activation in vivo in rats.

 Names

Name BR103

 BR103 Biological Activity

Description BR103 is a potent, metabolically stable and highly selective small molecule agonist of complement C3a receptor (C3aR) with EC50 of 22 ± 8  nM; displays high selectivity for C3aR over C5aR; induces paw oedema and mast cell activation in vivo in rats.
References References 1. Lohman RJ, et al. Nat Commun. 2017 Aug 24;8(1):351. View Related Products by Target Complement System

 Chemical & Physical Properties

Molecular Formula C24H28N6O3
Molecular Weight 448.527
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