JAK3-IN-12
Modify Date: 2025-08-27 18:13:52
JAK3-IN-12 structure
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Common Name | JAK3-IN-12 | ||
|---|---|---|---|---|
| CAS Number | 1430095-86-5 | Molecular Weight | 413.45 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H19N5O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of JAK3-IN-12JAK3-IN-12 (compound 15k) is a highly potent JAK3 inhibitor with an IC50 value of 9.5 nM. JAK3-IN-12 can be used for researching rheumatoid arthritis[1]. |
| Name | JAK3-IN-12 |
|---|
| Description | JAK3-IN-12 (compound 15k) is a highly potent JAK3 inhibitor with an IC50 value of 9.5 nM. JAK3-IN-12 can be used for researching rheumatoid arthritis[1]. |
|---|---|
| Related Catalog | |
| Target |
JAK3:9.5 nM (IC50) |
| In Vivo | Pharmacokinetic Parameters of JAK3-IN-12 in male C57BL/6J mice[1]. IV (1 mg/kg); PO (3 mg/kg) Tmax (h) 0.5 Cmax (ng/ml) 146±48 tmax (h) 1.85±0.43 CL (mL/min/kg), iv 40.37 ± 3.61 AUC0-α (μg/mL·h) 192 ± 56 F (%) 15 |
| References |
| Molecular Formula | C19H19N5O4S |
|---|---|
| Molecular Weight | 413.45 |