4-N-benzoylgeMcitabine

Modify Date: 2024-01-10 18:41:17

4-N-benzoylgeMcitabine Structure
4-N-benzoylgeMcitabine structure
 Common Name 4-N-benzoylgeMcitabine
CAS Number 142816-70-4 Molecular Weight 367.30
Density N/A Boiling Point N/A
Molecular Formula C16H15F2N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 4-N-benzoylgeMcitabine


N4-Benzoyl-2’-deoxy-2’,2’-diflurocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name N4-benzoyl-2'-deoxy-2',2'-difluorocytidine
Synonym More Synonyms

 4-N-benzoylgeMcitabine Biological Activity

Description N4-Benzoyl-2’-deoxy-2’,2’-diflurocytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C16H15F2N3O5
Molecular Weight 367.30
Exact Mass 367.09800
PSA 113.68000
LogP 0.45450

 Synonyms

N-benzoyl-2'-deoxy-2',2'-difluorocytidine
4-N-benzoylgemcitabine
N-benzoyl-2'-deoxy-2',2'-difluorocytidine hydrochloride
N-Bz-Gemcitabine
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