Silybin B

Modify Date: 2024-01-05 14:15:34

Silybin B structure	Common Name	Silybin B
	CAS Number	142797-34-0	Molecular Weight	482.436
	Density	1.5±0.1 g/cm3	Boiling Point	793.0±60.0 °C at 760 mmHg
	Molecular Formula	C₂₅H₂₂O₁₀	Melting Point	158-160℃ (methanol water )
	MSDS	USA	Flash Point	274.5±26.4 °C

Use of Silybin B

Silybin B, a flavonolignan separated from Silybum marianum, has anti-tumor activity. Silybin B is the most potent antifibrillogenic and anti-oligomeric component of silymarin and proposes it as a promising anti Alzheimer’s disease drug candidate[1][2].

Name	Silibinin
Synonym	More Synonyms

Description	Silybin B, a flavonolignan separated from Silybum marianum, has anti-tumor activity. Silybin B is the most potent antifibrillogenic and anti-oligomeric component of silymarin and proposes it as a promising anti Alzheimer’s disease drug candidate[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Neurological Disease
References	[1]. An-Shen Lin, et al. Cancer Preventive Agents. 7. Antitumor-Promoting Effects of Seven Active Flavonolignans from Milk Thistle (Silybum marianum.) on Epstein-Barr Virus Activation, Pharmaceutical Biology, 45:10, 735-738. [2]. Sciacca MFM, et al. Inhibition of Aβ Amyloid Growth and Toxicity by Silybins: The Crucial Role of Stereochemistry. ACS Chem Neurosci. 2017 Aug 16;8(8):1767-1778.

Description

Related Catalog

Research Areas >> Cancer

Research Areas >> Neurological Disease

References

[1]. An-Shen Lin, et al. Cancer Preventive Agents. 7. Antitumor-Promoting Effects of Seven Active Flavonolignans from Milk Thistle (Silybum marianum.) on Epstein-Barr Virus Activation, Pharmaceutical Biology, 45:10, 735-738.

[2]. Sciacca MFM, et al. Inhibition of Aβ Amyloid Growth and Toxicity by Silybins: The Crucial Role of Stereochemistry. ACS Chem Neurosci. 2017 Aug 16;8(8):1767-1778.

Density	1.5±0.1 g/cm3
Boiling Point	793.0±60.0 °C at 760 mmHg
Melting Point	158-160℃ (methanol water )
Molecular Formula	C₂₅H₂₂O₁₀
Molecular Weight	482.436
Flash Point	274.5±26.4 °C
Exact Mass	482.121307
LogP	2.59
Vapour Pressure	0.0±2.9 mmHg at 25°C
Index of Refraction	1.684
Storage condition	2-8°C

RIDADR	NONH for all modes of transport

Identification of diet-derived constituents as potent inhibitors of intestinal glucuronidation.

Drug Metab. Dispos. 42(10) , 1675-83, (2014)

Drug-metabolizing enzymes within enterocytes constitute a key barrier to xenobiotic entry into the systemic circulation. Furanocoumarins in grapefruit juice are cornerstone examples of diet-derived xe...

Isolation and purification of diastereoisomeric flavonolignans from silymarin by binary-column recycling preparative high-performance liquid chromatography.

J. Sep. Sci. 37(17) , 2300-6, (2014)

Silymarin extracted from Silybum marianum (L.) Gaertn consists of a large number of flavonolignans, of which diastereoisomeric flavonolignans including silybin A and silybin B, and isosilybin A and is...

MFCD03225424

SILIBININ A

(2R,3R)-3,5,7-Trihydroxy-2-[(2R,3R)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydro-4H-chromen-4-one

EINECS 245-302-5

[2R-[2a,3b,6(2R*,3R*)]]-2-[2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-4H-1-benzopyran-4-one

Silibinin

Silybin

Silybum Substance E6

33X338MNE4

MFCD00872186

4H-1-Benzopyran-4-one, 2-[(2R,3R)-2,3-dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-1,4-benzodioxin-6-yl]-2,3-dihydro-3,5,7-trihydroxy-, (2R,3R)-

Dura-Silymarin

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Silybin B
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

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