TMP780

Modify Date: 2024-01-19 23:04:09

TMP780 Structure
TMP780 structure
 Common Name TMP780
CAS Number 1422053-03-9 Molecular Weight 494.58
Density N/A Boiling Point N/A
Molecular Formula C31H30N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TMP780


TMP780 is an inverse agonist of RORγt with an IC50 of 13 nM. RORγt is a tractable drug target for the treatment of cutaneous inflammatory disorders[1].

 Names

Name TMP780

 TMP780 Biological Activity

Description TMP780 is an inverse agonist of RORγt with an IC50 of 13 nM. RORγt is a tractable drug target for the treatment of cutaneous inflammatory disorders[1].
Related Catalog
Target

IC50: 13 nM (RORγt)[1]

References

[1]. Skepner J, et al. Pharmacologic inhibition of RORγt regulates Th17 signature gene expression and suppresses cutaneous inflammation in vivo. J Immunol. 2014 Mar 15;192(6):2564-75.

 Chemical & Physical Properties

Molecular Formula C31H30N2O4
Molecular Weight 494.58
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Chemsrc provides TMP780(CAS#:1422053-03-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of TMP780 are included as well.>> amp version: TMP780

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