Piperazine adipate

Modify Date: 2024-01-06 21:32:31

Piperazine adipate structure	Common Name	Piperazine adipate
	CAS Number	142-88-1	Molecular Weight	232.27700
	Density	N/A	Boiling Point	338.5ºC at 760 mmHg
	Molecular Formula	C₁₀H₂₀N₂O₄	Melting Point	250ºC (Decomposes)
	MSDS	N/A	Flash Point	172.7ºC

Use of Piperazine adipate

Piperazine adipate is a potent broad spectrum anthelmintic against many common worm infections in mammals.

Name	Piperazine Adipate
Synonym	More Synonyms

Description	Piperazine adipate is a potent broad spectrum anthelmintic against many common worm infections in mammals.
Related Catalog	Signaling Pathways >> Anti-infection >> Parasite Research Areas >> Infection
In Vitro	Piperazine adipate (10 mM) causes mortality of A. galli and H. gallinae after a maximum of 30 min exposure, inhibits malate oxidation by 78%, and inhibits aldolase activity in both parasites. Piperazine adipate (10 mM) also inhibits cholinesterase activity by 96% in Ascaridia galli (A. galli) and 93% in Heterakis gallinae (H. gallinae). Piperazine adipate inhibits oxaloacetate reduction by 26% and 55% in A. galli and H. gallinae, resepctively[1].
References	[1]. Sharma RK, et al. Effect of parbendazole and piperazine adipate on the activity of some enzymes of Ascaridia galli and Heterakis gallinae. Vet Parasitol. 1987 May;24(3-4):211-20.

Boiling Point	338.5ºC at 760 mmHg
Melting Point	250ºC (Decomposes)
Molecular Formula	C₁₀H₂₀N₂O₄
Molecular Weight	232.27700
Flash Point	172.7ºC
Exact Mass	232.14200
PSA	98.66000
LogP	0.55280
Vapour Pressure	1.81E-05mmHg at 25°C
Stability	Stable. Combustible. Incompatible with strong oxidizing agents. May be light-sensitive.

Piperazine adipate MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MO1955000

CAS REGISTRY NUMBER :: 142-88-1

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C6-H10-O4.C4-H10-N2

MOLECULAR WEIGHT :: 232.32

WISWESSER LINE NOTATION :: T6N DNTJ &QV4VQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353 Vineuil, France) V.1- 1943- Volume(issue)/page/year: 13,539,1955

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,100,1982

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1640 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,100,1982

RIDADR	NONH for all modes of transport
RTECS	MO1955000
HS Code	2933599090

HS Code	2933599090
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

The effect of piperazine adipate and parbendazole on the carbohydrate metabolism of Ascaridia galli and Heterakis gallinae.

Angew. Parasitol. 28(4) , 207-10, (1987)

Carbohydrate metabolism of Ascardia galli and Heterakis gallinae was studied after their exposure in vitro to 10(-2) to 10(-5) M piperazine adipate and parbendazole for 10 to 60 min. Following treatme...

[Study of compounds with potential antiparasitic effect. V. Antihistaminics].

Wiad. Parazytol. 26(1) , 59-64, (1980)

[Experience with the prevention of enterobiasis in children from preschool institutions of the Zhitomir district].

Pediatriia (7) , 82-3, (1990)

PIPERAZINE ADIPATE

hexanedioic acid,piperazine

EINECS 205-569-0

MFCD00050650

DC Chemicals Limited
China
Product Name: Piperazine adipate
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Piperazine adipate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Price: $66/10mM*1mLinWater

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Piperazine adipate

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