Faropenem medoxomil
Modify Date: 2025-08-27 18:50:08
Faropenem medoxomil structure
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Common Name | Faropenem medoxomil | ||
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| CAS Number | 141702-36-5 | Molecular Weight | 397.40000 | |
| Density | 1.55 g/cm3 | Boiling Point | 622.3ºC at 760 mmHg | |
| Molecular Formula | C17H19NO8S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Faropenem medoxomilFaropenem daloxate is the first oral penem in a new class of beta-lactam antibiotics.IC50 Value: Target: AntibacterialFaropenem daloxate is useful for penem and antibiotics. Faropenem medoxomil has excellent in vitro activity against Streptococcus pneumoniae, Haemophilus influenzae and other key pathogens implicated in acute bacterial rhinosinusitis. Clinical studies have demonstrated that, in the treatment of acute bacterial rhinosinusitis in adults, 7 days of treatment with faropenem medoxomil is as clinically and bacteriologically effective as 10 days of treatment with cefuroxime axetil. One study showed faropenem medoxomil to be superior to cefuroxime axetil. Overall, the safety profile of faropenem medoxomil is similar to that of most comparators. |
| Name | (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate |
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| Synonym | More Synonyms |
| Description | Faropenem daloxate is the first oral penem in a new class of beta-lactam antibiotics.IC50 Value: Target: AntibacterialFaropenem daloxate is useful for penem and antibiotics. Faropenem medoxomil has excellent in vitro activity against Streptococcus pneumoniae, Haemophilus influenzae and other key pathogens implicated in acute bacterial rhinosinusitis. Clinical studies have demonstrated that, in the treatment of acute bacterial rhinosinusitis in adults, 7 days of treatment with faropenem medoxomil is as clinically and bacteriologically effective as 10 days of treatment with cefuroxime axetil. One study showed faropenem medoxomil to be superior to cefuroxime axetil. Overall, the safety profile of faropenem medoxomil is similar to that of most comparators. |
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| Related Catalog | |
| References |
| Density | 1.55 g/cm3 |
|---|---|
| Boiling Point | 622.3ºC at 760 mmHg |
| Molecular Formula | C17H19NO8S |
| Molecular Weight | 397.40000 |
| Exact Mass | 397.08300 |
| PSA | 144.72000 |
| LogP | 0.82500 |
| Vapour Pressure | 4.3E-18mmHg at 25°C |
| Index of Refraction | 1.642 |
| Storage condition | 2-8℃ |
| Faropenem medoxomil (USAN) |
| (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate |
| 4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester, (5R,6S)- |
| Faropenem daloxate |
| Orapem |
| (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl (5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydrofuran-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate |
| Faropenem medoxomil |
| A0026 |