(-)-Praeruptorin A

Modify Date: 2024-01-05 17:01:43

(-)-Praeruptorin A Structure
(-)-Praeruptorin A structure
Common Name (-)-Praeruptorin A
CAS Number 14017-71-1 Molecular Weight 386.40
Density 1.3±0.1 g/cm3 Boiling Point 486.8±45.0 °C at 760 mmHg
Molecular Formula C21H22O7 Melting Point N/A
MSDS N/A Flash Point 211.5±28.8 °C

 Use of (-)-Praeruptorin A


(-)-Praeruptorin A is a nature product that could be isolated from the roots of Peucedanum praeruptorum Dunn. (-)-Praeruptorin A relaxes ileum and tracheal smooth muscles by activating NO/cGMP signaling pathway. (-)-Praeruptorin A has dramatically therapeutic effects on hypertension mainly through acting as a Ca2+-influx blocker[1].

 Names

Name (9R,10R)-10-acetoxy-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-9-yl (Z)-2-methylbut-2-enoate
Synonym More Synonyms

 (-)-Praeruptorin A Biological Activity

Description (-)-Praeruptorin A is a nature product that could be isolated from the roots of Peucedanum praeruptorum Dunn. (-)-Praeruptorin A relaxes ileum and tracheal smooth muscles by activating NO/cGMP signaling pathway. (-)-Praeruptorin A has dramatically therapeutic effects on hypertension mainly through acting as a Ca2+-influx blocker[1].
Related Catalog
References

[1]. Xu Z, et, al. (+/-)-Praeruptorin A enantiomers exert distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis. Chem Biol Interact. 2010 Jul 30;186(2):239-46.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 486.8±45.0 °C at 760 mmHg
Molecular Formula C21H22O7
Molecular Weight 386.40
Flash Point 211.5±28.8 °C
Exact Mass 386.136566
PSA 92.04000
LogP 4.18
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.574

 Safety Information

Hazard Codes Xi

 Synonyms

(9R,10R)-10-Acetoxy-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-9-yl (2Z)-2-methyl-2-butenoate
2-Butenoic acid, 2-methyl-, (9R,10R)-10-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-9-yl ester, (2Z)-
(9R,10R)-10-(acetyloxy)-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-9-yl (2Z)-2-methylbut-2-enoate
(9R,10R)-10-Acetoxy-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-9-yl (2Z)-2-methylbut-2-enoate
(-)-Praeruptorin A