CL67

Modify Date: 2025-10-16 16:20:26

CL67 Structure
CL67 structure
Common Name CL67
CAS Number 1401242-86-1 Molecular Weight 670.81
Density N/A Boiling Point N/A
Molecular Formula C38H42N10O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CL67


CL67 is a potent hypoxia-inducible factor (HIF) pathway inhibitor. CL67 interferes G-quadruplex structures within promoter sequences. CL67 can be used in research of renal cancer[1].

 Names

Name CL67

 CL67 Biological Activity

Description CL67 is a potent hypoxia-inducible factor (HIF) pathway inhibitor. CL67 interferes G-quadruplex structures within promoter sequences. CL67 can be used in research of renal cancer[1].
Related Catalog
In Vitro CL67 (RCC4 和 RCC4VHL 细胞) 以剂量依赖性方式抑制 HIF-1α 蛋白[1]。
References

[1]. Sarah JW, et, al. CL67: A novel G-quadruplex stabilising agent inhibits the HIF-1 pathway. Cancer Res (2011) 71 (8_Supplement):4506.

 Chemical & Physical Properties

Molecular Formula C38H42N10O2
Molecular Weight 670.81
InChIKey WXTDHADVBWQHLW-UHFFFAOYSA-N
SMILES CCN(CC)CC(=O)Nc1cccc(-n2cc(-c3ccc4ccc(-c5cn(-c6cccc(NC(=O)CN(CC)CC)c6)nn5)cc4c3)nn2)c1
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