CL67

Names

[ CAS No. ]:
1401242-86-1

[ Name ]:
CL67

Biological Activity

[Description]:

CL67 is a potent hypoxia-inducible factor (HIF) pathway inhibitor. CL67 interferes G-quadruplex structures within promoter sequences. CL67 can be used in research of renal cancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> HIF/HIF Prolyl-Hydroxylase

[In Vitro]

CL67 (RCC4 和 RCC4VHL 细胞) 以剂量依赖性方式抑制 HIF-1α 蛋白[1]。

[References]

[1]. Sarah JW, et, al. CL67: A novel G-quadruplex stabilising agent inhibits the HIF-1 pathway. Cancer Res (2011) 71 (8_Supplement):4506.

Chemical & Physical Properties

[ Molecular Formula ]:
C38H42N10O2

[ Molecular Weight ]:
670.81

Related Compounds

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