2-Methyl-5-vinylpyridine

Modify Date: 2024-01-05 18:09:39

2-Methyl-5-vinylpyridine Structure
2-Methyl-5-vinylpyridine structure
Common Name 2-Methyl-5-vinylpyridine
CAS Number 140-76-1 Molecular Weight 119.164
Density 1.0±0.1 g/cm3 Boiling Point 175.5±9.0 °C at 760 mmHg
Molecular Formula C8H9N Melting Point 180 °C (dec.)(lit.)
MSDS N/A Flash Point 56.6±10.9 °C

 Names

Name 2-Methyl-5-vinylpyridine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 175.5±9.0 °C at 760 mmHg
Melting Point 180 °C (dec.)(lit.)
Molecular Formula C8H9N
Molecular Weight 119.164
Flash Point 56.6±10.9 °C
Exact Mass 119.073502
PSA 12.89000
LogP 1.92
Vapour Pressure 1.5±0.3 mmHg at 25°C
Index of Refraction 1.555

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UT2975000
CHEMICAL NAME :
Pyridine, 5-ethenyl-2-methyl-
CAS REGISTRY NUMBER :
140-76-1
BEILSTEIN REFERENCE NO. :
0106229
LAST UPDATED :
199712
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C8-H9-N
MOLECULAR WEIGHT :
119.18
WISWESSER LINE NOTATION :
T6NJ B1 E1U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0546451 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1300 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
189 mg/m3/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,88,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1290 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,88,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
775 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,88,1982
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
213 mg/m3/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,88,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
532 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,88,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
800 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 39(4),86,1974 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 2 mg/m3;Skin JAN 1993

 Safety Information

Hazard Codes T+
RIDADR 2810
Packaging Group III
Hazard Class 6.1(b)
HS Code 2933399090

 Synthetic Route

~46%

2-Methyl-5-vinylpyridine Structure

2-Methyl-5-viny...

CAS#:140-76-1

Literature: MEDIVATION TECHNOLOGIES, INC.; HUNG, David, T.; PROTTER, Andrew, Asher; JAIN, Rajendra, Parasmal; CHAKRAVARTY, Sarvajit; GIORGETTI, Marco Patent: WO2010/51503 A1, 2010 ; Location in patent: Page/Page column 249 ; WO 2010/051503 A1

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2-Methyl-5-vinylpyridine Structure

2-Methyl-5-viny...

CAS#:140-76-1

Literature: WO2009/110985 A2, ; Page/Page column 63 ; WO 2009/110985 A2

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2-Methyl-5-vinylpyridine Structure

2-Methyl-5-viny...

CAS#:140-76-1

Literature: US2611769 , ;

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2-Methyl-5-vinylpyridine Structure

2-Methyl-5-viny...

CAS#:140-76-1

Literature: WO2009/111540 A1, ;

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

5-20-06-00218 (Beilstein Handbook Reference)
2-methyl-5-vinyl pyridine
Pyridine, 5-ethenyl-2-methyl-
EINECS 205-432-5
Pyridine, 2-methyl-5-vinyl
5-vinyl-2-methylpyridine
2-Methyl-5-vinylpridine
2,5-Methylvinylpyridine
Pyridine,2-methyl-5-vinyl
5-Ethenyl-2-methypyridine
2-Methyl-5-vinyl-pyridin
5-Vinyl-2-picoline
2-Picoline,5-vinyl
methyl vinyl pyridine
5-ethenyl-2-methylpyridine
Pyridine,5-ethenyl-2-methyl
6-methyl-3-vinylpyridine
2-Methyl-5-vinylpyridine