Benzyl chloroacetate

Modify Date: 2024-01-02 18:38:07

Benzyl chloroacetate Structure
Benzyl chloroacetate structure
Common Name Benzyl chloroacetate
CAS Number 140-18-1 Molecular Weight 184.620
Density 1.2±0.1 g/cm3 Boiling Point 252.8±15.0 °C at 760 mmHg
Molecular Formula C9H9ClO2 Melting Point 90ºC
MSDS Chinese USA Flash Point 117.9±15.8 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name Benzyl 2-chloroacetate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 252.8±15.0 °C at 760 mmHg
Melting Point 90ºC
Molecular Formula C9H9ClO2
Molecular Weight 184.620
Flash Point 117.9±15.8 °C
Exact Mass 184.029114
PSA 26.30000
LogP 2.20
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.525
Water Solubility insoluble

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AF8750000
CHEMICAL NAME :
Acetic acid, chloro-, benzyl ester
CAS REGISTRY NUMBER :
140-18-1
BEILSTEIN REFERENCE NO. :
2091502
LAST UPDATED :
199701
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C9-H9-Cl-O2
MOLECULAR WEIGHT :
184.63
WISWESSER LINE NOTATION :
G1VO1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 8,99,1956

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS AF8750000
HS Code 2915400090

 Synthetic Route

 Customs

HS Code 2915400090
Summary 2915400090 mono-, di- or trichloroacetic acids, their salts and esters

 Articles3

More Articles
Synthesis and anti-herpes simplex activity of analogues of phosphonoacetic acid.

J. Med. Chem. 20(5) , 660-3, (1977)

The synthesis of monoesters (P and C) of phosphonoacetic acid (PA) is given. The carboxyl esters were prepared by two methods: the reaction of chloroacetates with tris(trimethylsilyl) phosphite, follo...

Influence of the substrate structure on carboxypeptidase Y catalyzed peptide bond formation. Breddam K, et al.

Carlsberg Res. Commun. 45(5) , 361-67, (1980)

Stereoselective total syntheses of the (±)-di-O-methyl ethers of agatharesinol, sesquirin-A, and hinokiresinol, and of (±)-tri-O-methylsequirin-E, characteristic norlignans of coniferae. Beracierta AP and Whiting DA.

J. Chem. Soc. Perkin Trans. I 10 , 1257-63, (1978)

 Synonyms

benzyl monochloroacetate
chloroacetic acid benzyl ester
Acetic acid, 2-chloro-, phenylmethyl ester
Acetic acid,chloro-,phenylmethyl ester
MFCD00157062
Benzyl α-chloroacetate
Benzyl monochloracetate
Benzyl chloroacetate
chloroacetic acid phenylmethyl ester
Monochloroacetate
EINECS 205-400-0
BENZYL 2-CHLOROACETATE
Acetic acid,chloro-,benzyl ester
phenylmethyl 2-chloroacetate