3,6,9-Trioxaundecanedioic acid

Modify Date: 2024-01-06 14:48:03

3,6,9-Trioxaundecanedioic acid Structure
3,6,9-Trioxaundecanedioic acid structure
Common Name 3,6,9-Trioxaundecanedioic acid
CAS Number 13887-98-4 Molecular Weight 222.193
Density 1.3±0.1 g/cm3 Boiling Point 443.7±30.0 °C at 760 mmHg
Molecular Formula C8H14O7 Melting Point N/A
MSDS N/A Flash Point 178.3±18.1 °C

 Use of 3,6,9-Trioxaundecanedioic acid


369-Trioxaundecanedioic Acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 3,6,9-Trioxaundecanedioic acid
Synonym More Synonyms

 3,6,9-Trioxaundecanedioic acid Biological Activity

Description 369-Trioxaundecanedioic Acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 443.7±30.0 °C at 760 mmHg
Molecular Formula C8H14O7
Molecular Weight 222.193
Flash Point 178.3±18.1 °C
Exact Mass 222.073959
PSA 102.29000
LogP -1.96
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.474

 Safety Information

Hazard Codes Xi: Irritant;
Risk Phrases 41
Safety Phrases 26-39
RIDADR UN 1760
Packaging Group III
HS Code 2918990090

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

2,2'-[Oxybis(2,1-ethanediyloxy)]diacetic acid
2-[2-[2-(carboxymethoxy)ethoxy]ethoxy]acetic acid
2,2'-[Oxybis(ethane-2,1-diyloxy)]diacetic acid
Acetic acid, 2,2'-[oxybis(2,1-ethanediyloxy)]bis-