Diphlorethohydroxycarmalol
Modify Date: 2024-01-10 10:22:36
Diphlorethohydroxycarmalol structure
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Common Name | Diphlorethohydroxycarmalol | ||
|---|---|---|---|---|
| CAS Number | 138529-04-1 | Molecular Weight | 512.38 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H16O13 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DiphlorethohydroxycarmalolDiphlorethohydroxycarmalol, a kind of phlorotannin, is an orally active α-glucosidase and α-amylase inhibitor with IC50s of 0.16 mM and 0.53 mM, respectively. Diphlorethohydroxycarmalol has anti-diabetic activities[1]. |
| Name | diphlorethohydroxycarmalol |
|---|---|
| Synonym | More Synonyms |
| Description | Diphlorethohydroxycarmalol, a kind of phlorotannin, is an orally active α-glucosidase and α-amylase inhibitor with IC50s of 0.16 mM and 0.53 mM, respectively. Diphlorethohydroxycarmalol has anti-diabetic activities[1]. |
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| Related Catalog | |
| Target |
IC50: 0.16 mM (α-glucosidase) and 0.53 mM (α-amylase) [1] |
| In Vivo | The increase of postprandial blood glucose levels are significantly suppressed in the Diphlorethohydroxycarmalol-administered group than those in the streptozotocin-induced diabetic or normal mice. Moreover, the area under curve (AUC) is significantly reduced via Diphlorethohydroxycarmalol (100 mg/kg; p.o.) administration (2022 versus 2210 mmol x min/lL) in the diabetic mice as well as it delays absorption of dietary carbohydrates[1]. |
| References |
| Molecular Formula | C24H16O13 |
|---|---|
| Molecular Weight | 512.38 |
| Exact Mass | 512.05900 |
| PSA | 218.99000 |
| LogP | 4.51960 |
| 7-(3,5-Dihydroxy-phenoxy)-3-(2,4,6-trihydroxy-phenoxy)-dibenzo[1,4]dioxine-1,2,6,8-tetraol |